We also demonstrated that ABCs have a distinct chemokine receptor profile, with high expression of CXCR3 and CXCR2, both encoding receptors, which recruit cells to inflamed tissues, and CX3CR1, which has been linked to the migration of cells to the RA synovium [38], and low expression of CXCR4, CXCR5 and CCR7, which mediate recruitment to lymph nodes. The gene discussed is CXCR4; the disease is rheumatoid arthritis.