Previous studies have shown that the main pathological features of AD are extracellular senile plaques composed of aggregated β-amyloid (Aβ) peptides, intracellular neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein, Aβ cerebral amyloid angiopathy A, and neuronal loss caused by Aβ deposition on the vascular wall [5, 6]. This evidence concerns the gene MAPT and Alzheimer disease.