From the 46 genes that presented promoter interacting regions overlapping significant SSc‐associated GWAS SNPs and enhancer regions, we identified a total of 21 drugs of interest in SSc that target protein products that are in strong protein–protein interaction with 13 of those genes (5 of them specific for CD4+ T cells interactions) (Table 2). The gene discussed is CD4; the disease is systemic sclerosis.