We also extracted the top 50 most significant genes that were positively or negatively associated with CXCL2 in STAD, as shown in Figure 8B and C. The top five most significantly CXCL2-associated genes were IL8, ZC3H12A, NFKBIZ, CFB, and CSF3 (Fig. 9A–E). Here, ZC3H12A is linked to gastric adenocarcinoma.