From the enrichment analysis results, it can be seen that the bioactive components of Gancao Xiexin decoction act on multiple targets to treat BD in a variety of ways, involving a variety of signaling pathways, such as lipid and atherosclerosis, fluid shear stress, atherosclerosis, AGE-RAGE signal pathway, TNF signal pathway, and IL-17 signaling pathway. This evidence concerns the gene TNF and atherosclerosis.