CD34 is usually positive for SFTs/HPCs, but weakly positive in 15% to 60% of meningiomas.[19,20] The positive rate of EMA in meningiomas is as high as 89.7%, so EMA is widely considered as a useful marker for the diagnosis of meningiomas.[21] However, it may also be positive in 0-20% SFTs/HPCs.[20,22] Therefore, detection of nuclear expression of STAT6 has been highly valued at present, because compared with these markers, the sensitivity and specificity of STAT6 to SFT can reach 96% and 100% respectively. The gene discussed is STAT6; the disease is meningioma.