Factors in the univariate survival analysis (P < 0.05) were incorporated into the Cox regression model for multivariate analysis, delineating the following five independent prognostic factors: KPS [hazard rate (HR) = 0.321, 95% CI: 0.147–0.700, P = 0.004], preoperative tumor markers (HR = 3.604, 95% CI: 1.512–8.591, P = 0.004), Ki-67 (HR = 10.603, 95% CI: 1.117–77.700, P = 0.020), SAEs (HR = 2.122, 95% CI: 1.003–4.307, P = 0.013), and red blood cell infusion (HR = 2.079, 95% CI: 1.003–4.307, P = 0.049). This evidence concerns the gene MKI67 and neoplasm.