Most studies have shown that there are abnormal expression levels and related signaling pathways of CLCA2 in malignant tumors, and it is closely related to tumor invasion and metastasis [7, 23, 24], CLCA2 is down regulated in cervical cancer [25, 26], but its role and exact regulatory mechanism in cervical cancer are still unclear. This evidence concerns the gene CLCA2 and neoplasm.