NLRP3 and Anxiety: CEE induced slower growth (Fig. 3b), anxiety-like and depressive-like behavior (less time spent in the central area of the OFT and open arms of the EPM, increased immobility time and an early onset of immobility in the FST, Fig. 3e–h), and neuronal damage in the hippocampus (reduced expression of synaptic proteins and neurotrophic proteins, Fig. 3o, p) only in the mice transfected with Con-shRNA but not NLRP3-shRNA.