Consistent with the prior result (Figure 3A–D), Tlr7−/y pDC in infected chimeras exhibited long tracks and did not arrest while WT pDC had much shorter tracks and arrested, establishing that TLR7 signaling intrinsic to pDC, is required for them to stop during infection (Figure 3E, F and Figure 3—video 3). This evidence concerns the gene TLR7 and infection.