STING was originally identified as a cytosolic nucleic-acid sensor, which triggering leads to the induction of a robust type I IFN response via IRF3 and NFkB, and a rapid antiviral state that enables the control of viral infections (Zhong et al., 2008; Ishikawa and Barber, 2008). This evidence concerns the gene NFKB1 and viral infectious disease.