Apart from that, Zhong et al. [68], in an attempt to further explore the implication of MMP-9 in stroke prognosis, concluded that the serum MMP-9 concentration in the acute phase of ischemic stroke was positively associated with the risk of mortality and major disability at 3 months, supporting the use of MMP-9 as a potential prognostic biomarker poststroke. The gene discussed is MMP9; the disease is ischemic stroke.