NBS also produces incidental findings (IFs), namely detection of more babies who are heterozygote carriers [8,9,10], and others have a condition known as CFTR-related metabolic syndrome (CRMS) or CF screen positive, inconclusive diagnosis (CFSPID) [11,12]. The gene discussed is CFTR; the disease is CFTR-related metabolic syndrome/CF screen positive, inconclusive diagnosis.