When we analyzed the changes in the measured data before and after surgery within each group (LC and OC), we found that in the LC group (Table 1), there was a significant increase between values at baseline (A1) and at 24 h (A2) of IL-6 (p < 0.001), IL-8 (p < 0.001), ferritin (p < 0.001) (Figure 1), leukocytes (p < 0.001), neutrophil (N) percentage (p < 0.001) and N/L ratio (p < 0.001) (Figure 2) and CRP (p < 0.001) and a significant decrease in TNF (p < 0.001), Hb (p < 0.001) (Figure 1), lymphocyte percentage (p < 0.001), albumin (p < 0.001) and prothrombin (p < 0.001). This evidence concerns the gene F2 and laryngotracheoesophageal cleft.