Another SH from the same cluster, Spatholobus suberectus Dunn, was reported that (-)-Sativan, a naturally isolated isoflavone from Spatholobus suberectus Dunn, could inhibit PD-L1 expression and epithelial-to-mesenchymal transition by up-regulating miR-200c in triple-negative breast cancer cells (Peng et al., 2020). The gene discussed is CD274; the disease is triple-negative breast carcinoma.