NOX4 and central nervous system cancer: Supplementary Table S1 lists patient information. Regarding the prognostic value of NOX4 in glioma, the CGGA and TCGA Low-Grade Glioma datasets showed that patients with glioma with a higher NOX4 expression had worse overall survival than those with a lower NOX4 expression (Figures 1G,H). These results suggested that NOX4 was upregulated and acted as a potential oncogene in glioblastoma.