Furthermore, pieces of clinical studies also showed that miRNA-424 (Li et al., 2018b) and miRNA-99a-5p (Zhao et al., 2017) levels in circulating immune cells and circulating lncRNA H19 (Wang et al., 2017) levels possessed diagnostic potential for ischemic stroke; miRNA-128 levels in circulating lymphocytes of AIS patients were correlated with stroke severity (Liu et al., 2019); and miRNA-494 in circulating neutrophils could predict the clinical outcomes of AIS patients (Li et al., 2020). This evidence concerns the gene H19 and Stroke.