Resveratrol-activated human TRPA1 can induce the entry of Ca2+ and lead to the expression of growth factors, which may regulate growth and migration and inhibit apoptosis in cancer-associated fibroblasts (CAFs) through secretion of HGF and VEGF and the calcineurin/NFAT pathway, which should be further researched for confirmation (Vancauwenberghe et al., 2017). The gene discussed is TRPA1; the disease is cancer.