Meanwhile, morusin, kuwanon C and morusyunnansin L are probably the important ingredients of MLF in hypoglycemia, which may function by regulating key targets, including ADORA1, AKT serine/threonine kinase 1 (AKT1), PPARγ and glycogen synthase kinase-3 beta (GSK3β). The gene discussed is GSK3B; the disease is Hypoglycemia.