Moreover, ginsenoside Rg3 also enhance the chemotherapy sensitivity of DDP-resistant human lung cancer cell and PTX-resistant TNBC by downregulating MDR-mediated proteins (including P-glycoprotein (P-gp), multidrug resistance-related protein (MPR1) and lung resistance protein 1 (LPR1)) (Liu et al., 2018) and inhibiting NF-κB signaling pathway, respectively (Yuan et al., 2017). The gene discussed is IGF2R; the disease is lung carcinoma.