Daidi Fan’s research shows that ginsenoside Rh4 can not only effectively inhibit the proliferation of S-phase cells, but also induce apoptosis by reducing Bcl-2, increasing Bax and activating caspase-8, caspase-3 and PARP, thereby inhibiting BC cells growth (Duan et al., 2018). This evidence concerns the gene CASP8 and breast cancer.