PVT1 and epilepsy: Results of pre-clinical studies showed that the expressions of LncRNA H19 and LncRNA X inactive specific transcript (XIST) were up-regulated, while the expressions of LncRNA PVT1, LncRNA CACS2, and LncRNA UCA1 were down-regulated in epilepsy animal or cell models (Han et al., 2018a; Wang et al., 2020; Zhang et al., 2021).