Moreover, GAS5 could epigenetically suppress the transcriptional miR-219 expression, and knockdown of GAS5 could dramatically promote the cell proliferation of epileptic cells and suppress the inflammation and apoptosis processes, which could be reversed by inhibition of miR-219, suggesting a regulation role of LncRNA GAS5 in the inflammatory response of epilepsy via its effect on miR-219 (Zhao et al., 2022). The gene discussed is GAS5; the disease is epilepsy.