ABAT and Seizure: More importantly, vigabatrin, a second-generation antiepileptic drug with a remarkable effect against infantile spasms and focal seizures, is a structural analog of GABA that irreversibly inhibits GABA-transaminase (GABA-T) and increase brain levels of GABA (O’Callaghan et al., 2017; Knupp et al., 2022).