Compared to healthy controls, pRNFL thinning has also been reported in subjects with PSP (Stemplewitz et al., 2017), TDP-43 (Ward et al., 2014), a pathologically heterogeneous group of subjects with FTD (Ferrari et al., 2017), and ALS (Ringelstein et al., 2014; Mukherjee et al., 2017; Rohani et al., 2018). The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.