The study of domestic scholars Feige et al. on 66 patients with Ig G-type MM has shown that patients with Ig G ≤64 g/L are distinctly superior to patients with Ig G >64 g/L in terms of overall survival and progression-free survival [16], which further confirmed that the abnormal immunoglobulin level was an intuitive reflection of monoclonal hyperplasia degree in MM, as an indicator to evaluate the disease state and reflect the degree of tumor load. The gene discussed is GAN; the disease is neoplasm.