In this study, we summarized our results with the Amoydx Super-ARMS EGFR Mutation Detection Kit (Amoy Diagnostics Co., Ltd., Xiamen, China) test and we also compared the performance of the AmoyDx and the cobas EGFR Mutation test v2 (cobasv2; Roche Molecular Systems, Pleasanton, CA, United States) in peripheral plasma samples of NSCLC patients. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.