Both the annual rate of MG-related hospitalization and ER visit were also significantly higher in the titin+ group [0.2 (0.1–0.6) and 0.1 (0–0.2) per year, respectively] than those in the titin– group [0 (0–0.2) and 0 (0–0) per year, p = 0.004 and p = 0.006, respectively]. This evidence concerns the gene TTN and myasthenia gravis.