In addition, genes from GreenYellow, which were found to have the highest association with uncontrolled hypertension (r = 0.35, p = 0.03, soft threshold beta = 12, Figures 7A,B) were involved in hemostasis, smooth muscle contraction, regulation of cell adhesion, Ras protein signal transduction, and so on, which were broadly regulated by SRF and TCF4. The gene discussed is SRF; the disease is Hypertension.