Additional adjustment of model 2 by serial C-reactive protein, anti-Xa level, fibrinogen, SOFA score, pulmonary embolism and deep venous thrombosis, showed lower ETP in the 2nd [−724 nM min (95%CI: −1,143 to −304), the 3rd [−581 nM min (95%CI: −967 to −196)], and the 5th [−468 nM min (95%CI: −932 to −5)] weeks after intubation compared to the first week (Table 3, model 3). This evidence concerns the gene CRP and pulmonary embolism.