Compared with the sham group, the BD group showed significantly increased expression of Klotho at the protein (5.22 ± 1.25 vs. 2.39 ± 0.97, P = 0.012) and mRNA levels (4.87 ± 0.56 vs. 1.03 ± 0.20, P < 0.001, Figure 5C). This evidence concerns the gene KL and Behcet disease.