GPBAR1 and Behcet disease: The expression of BA-specific receptors FXR and TGR5 in the hypothalamus at the protein level (0.78 ± 0.01 vs. 0.82 ± 0.04, P = 0.570; 0.84 ± 0.06 vs. 0.87 ± 0.08, P = 0.059) and mRNA level (0.81 ± 0.23 vs. 0.94 ± 0.21, P = 0.413; 0.97 ± 0.23 vs. 0.98 ± 0.17, P = 0.949) was not significantly changed between the BD group and the sham group (Figure 5A).