The death of patients with septic shock was taken as the dependent variable, and the age, SOFA score, APACHE II score, ICU length of stay, the number of MODS, serum albumin, MAP, 24-hour urine volume, Pcv-aCO2, Pcv-aCO2/Ca-cvO2, and lactic acid determination values on the third day of ICU stay were taken as independent variables in the univariate analysis. The gene discussed is ALB; the disease is septic shock.