GPT and prediabetes syndrome: Over seven months, both liraglutide and orlistat led to a reduction of weight (7.7 kg with liraglutide vs 3.3 kg with orlistat), systolic blood pressure, fasting glucose level, LDL cholesterol, and alanine transaminase. 64.7% of participants taking liraglutide lost 5% or more of their baseline weight vs 27.4% with orlistat. Liraglutide also led to lower prediabetes rates compared to orlistat.