1.Autism spectrum disorder: de novo c.991_992delAT (NM_014969.6); p.I331Ffs*16 (NP_055784.3) (Callaghan et al., 2019)2.The neuroanatomical deficits associated with Wdr47 KO cause hyperactivity and inappropriate sensory motor gating in both male and female mice (Kannan et al., 2017).3.The overall brain size of Wdr47tm1a/tm1a mice was reduced, indicating initial microcephaly that worsened postnatally (Kannan et al., 2017).4.Mutations in 27 WDR genes (∼9 %) have been linked to brain disorders especially intellectual disability related to corpus callosum defects (Kannan et al., 2017). This evidence concerns the gene WDR47 and brain disorder.