VEGFA and pachyonychia congenita: In addition to the decreased accumulation of miR-29b in HUVECs treated with GW4869, our studies of HUVEC tube formation and migration abilities, coupled with the effects of a potent angiogenesis stimulator (VEGF), showed that the inhibition of HUVEC angiogenesis by exosomes from PC cells transfected with miR-29b mimics could be reversed by GW4869.