Previous studies have shown that Kv1.3 in T lymphocytes is involved in the pathogenesis of renal diseases, including acute glomerulonephritis, lupus nephritis and chronic kidney disease, and that its expression would contribute to disease progression (Grgic et al., 2009b; Hyodo et al., 2010; Kazama et al., 2012; Khodoun et al., 2020). The gene discussed is KCNA3; the disease is kidney disorder.