TTR can interact with hnRNPA2B1 to form a TTR-hnRNPA2B1 complex, which plays a critical role in TTR’s anti-angiogenesis function in hyperglycemia via the STAT4/miR-223e3p/FBXW7 signaling pathway (Gu et al., 2021). The gene discussed is TTR; the disease is Hyperglycemia.