CASP3 and breast cancer: After topological analysis, the chi values of degree ≥ 85, CC ≥ 0.744, and BC ≥ 200.368 were selected as the screening conditions, and the targets that met the above three chi values were selected as key targets, mainly including TNF, IL-6, ALB, AKT1, IL-1Β, TP53, CASP3, PTGS2, JUN, and STAT3 (Table 4).