Another highly expressed miRNA is miR-30a-5p known to negatively regulate cell growth, migration, invasion, and metastasis, autophagy in chronic myelogenous leukemia, and TGF-b1-induced epithelial-mesenchymal transition in cancer (Jiang L. H. et al., 2018). The gene discussed is TGFB1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.