In recent years, various human Pleckstrin and sec7 domain-containing 3 (PSD3) have been believed to be related to some tumors, like acute myeloid leukemia (Walker et al., 2021), breast cancer metastasis (Thomassen et al., 2009), astrocytoma progression (van den Boom et al., 2006). Here, PSD3 is linked to breast carcinoma.