In recent years, various human Pleckstrin and sec7 domain-containing 3 (PSD3) have been believed to be related to some tumors, like acute myeloid leukemia (Walker et al., 2021), breast cancer metastasis (Thomassen et al., 2009), astrocytoma progression (van den Boom et al., 2006). This evidence concerns the gene PSD3 and breast cancer.