HOXC4 and neoplasm: In contrast, HOXC4 expression was negatively correlated with cell cycle-related pathways and specific metabolic pathways, such as disease of DNA repair, peroxisomal lipid metabolism, cellular lipid catabolic process, epithelial to mesenchymal transition, etc. Taken these results together, HOXC4 expression may be linked with a variety of biological functions and signaling pathways, especially concerning tumor immunity, cell cycle and metabolic issues.