Previously, a large number of RPGR variants were reported to result in a Severe “Male Pattern” in female carriers (Nanda et al., 2018; Salvetti et al., 2021) and variants c.3001G>T (p. Glu945*), c.2730_2731del (p. Glu911Glyfs*167), and c.607G>C (p. Ala203Pro) were reported to be associated with RP phenotypes in female carriers. Here, RPGR is linked to retinitis pigmentosa 1.