Finally, through multivariate Cox regression analysis, we screened out 9 neutrophil-related genes (PDLIM3, KLF2, ROR2, PGF, EFNB1, PDZD4, PLN, PCDH17, DOK5, Supplementary Table S4) that are beneficial for predicting the prognosis of HCC patients. Here, EFNB1 is linked to hepatocellular carcinoma.