Earlier genetic analyses for ALR-derived resistance to T1D identified mt-Nd2 of the mtDNA as well as loci on Chr 17 (Idd16), Chr 8 (Idd22), and Chr 3 (Susp) (Mathews et al., 2003; Mathews et al., 2005; Pomerleau et al., 2005). The gene discussed is MT-ND2; the disease is type 1 diabetes mellitus.