Thus, the relationship between CD274/PDCD1LG2 and the degree of immune cell infiltration was explored, based on TIMER, the data showed that CD274/PDCD1LG2 levels were positively associated with macrophages, dendritic cells, neutrophils, and CD8+ T cells in most cancers (Supplementary Table S1). The gene discussed is PDCD1LG2; the disease is cancer.