In ACC (p = 0.036), KIRC (p = 0.012), OV (p = 0.028), and SKCM (p < 0.001), patients with high CD274 expression had longer OS than those with low CD274 expression (Figures 4A,B,E,F), but in LAML (p = 0.045) and LGG (p < 0.001), patients with high CD274 expression exhibited shorter OS (Figures 4C,D). The gene discussed is CD274; the disease is adrenal cortex carcinoma.