Using the same cohort, PBSC-MRD detected by qPCR with MES NB-mRNAs (POSTN or PRRX1 mRNA), but not ADRN NB-mRNAs (CHRNA3, DBH, DDC, PHOX2B, or TH mRNA), was reported to be significantly associated with EFS and OS of high-risk NB patients [26, 27]. This evidence concerns the gene CHRNA3 and neuroblastoma.