Against ovarian cancer HEY cell xenografts, three treatments with the CDCP1 targeted ADCs almost completely blocked tumor growth for the duration of the assay, while three treatments of the chemotherapy carboplatin had little impact on tumor growth in comparison with vehicle and IgG-MMAE treated tumors the growths of which were uncontrolled (Figure 5B). The gene discussed is CDCP1; the disease is ovarian carcinoma.