CDCP1 and colorectal cancer: We next examined the efficacy of ch10D7-MMAE, in comparison with 10D7-MMAE and three standard-of-care chemotherapies, in in vivo models of pancreatic, ovarian, and colorectal cancer that express cell surface CDCP1 at levels above the identified threshold of 1×105 receptors per cell (Figure 3D) and are responsive to ch10D7-MMAE in vitro (Figure 3B).