CDCP1 and malignant colon neoplasm: ch10D7-89Zr was effective at detecting CDCP1-expressing PDAC xenografts in mice, and ch10D7-MMAE displayed robust anti-tumor effects in vivo against xenografts of PDAC, and ovarian and colon cancer, significantly prolonging mouse survival in comparison with controls including three chemotherapeutic agents widely used clinically.