In addition, because we and others have shown that a region of CDCP1 can be shed from the cell surface and detected in colon cancer patient serum and function as a predictive biomarker of lung cancer onset 11, 34, 35, the detection of cell-shed CDCP1 may be suitable for selection of cancer patients suitable for CDCP1-targeted therapies. This evidence concerns the gene CDCP1 and lung cancer.