To explore whether AEG-1 palmitoylation is linked to HCC tumorigenesis, AEG-1-WT or AEG-1-MT was expressed in Huh7 and HepG2 cells (Figure 1I), and the results showed that the expression of AEG-1-MT boosted cell growth as compared to the control (transfected with empty vector), while the expression of AEG-1-MT further accelerated cell proliferation as compared to that of the WT AEG-1 (Figure 1J). The gene discussed is MTDH; the disease is hepatocellular carcinoma.