To investigate the correlations between zDHHC6 and HCC tumorigenesis, a tissue microarray containing 133 pairs of HCC tumor and adjacent normal tissues was analyzed by IHC and the results showed that zDHHC6 expression (mainly within the cytoplasm) was significantly lower in HCC tumors than that of the adjacent normal tissues (Figure 3I-J). Here, ZDHHC6 is linked to hepatocellular carcinoma.