CASP3 and nonpapillary renal cell carcinoma: The expression of apoptosis markers (caspase-3, cleaved caspase-3, and Bax) and the cell cycle marker cyclin D1 in ccRCC cells was investigated by western blotting, the results also displayed that CCRK can recover the inhibitory effect of miR-335-5p on ccRCC cell proliferation (Figures 6(g) and 6(i)).