TGFB1 and neoplasm: Some scholars stated that resveratrol modulated the changes of Treg population and tumor-related immune cytokines, as reflected by the downregulation of the CD8+CD122+ Tregs, TGF-β1, and IL-10 and the upregulation of IFN-γ-expressing CD8+T cells, TNF-α, and IFN-γ in the tumor and peripheral lymphoid organs of tumor-bearing mice [48].