M2 macrophages have been reported to promote tumor growth by a variety of mechanisms, including the production of immunomodulators such as IL-10, IL-6, and TGF-1, as well as the recruitment of Th2 and Treg cells via anti-inflammatory chemokines such as CXCL17, 22, and 24 [30–32]. The gene discussed is IL10; the disease is neoplasm.