Next, we determined the localization of RBP7 expression in breast cancer, the functional enrichment of its coexpressed genes, and the association between the mRNA expression and DNA methylation of RBP7. Then, we explored the association between RBP7 and multiple molecular subtypes of breast cancer and the significant KEGG pathways involved in RBP7 in ER+ breast cancer. Here, RBP7 is linked to breast carcinoma.