Although there was no association between PD-L1 and p16 or p53, there was a significant positive correlation between CD8 expression to tumor and stroma PD-L1 positivity score (ANOVA p=0.0003 and p<0.000, respectively) and expression (ANOVA p<0.000 and p=0.001, respectively). Here, TP53 is linked to neoplasm.