Thus, we studied whether ultrasound radiomics could be utilized as a predictive biomarker for the identification of Ki-67 status, and the aim of this study was to develop and validate an ultrasound-based radiomics nomogram model by integrating the clinical risk factors and ultrasound radiomics score (Rad-Score) to predict the Ki-67 status in patients with BC. Here, MKI67 is linked to breast cancer.